Research Article
Correlation Between Vitamin D Levels and Dyslipidemia in Patients at Fann University Hospital
Issue:
Volume 13, Issue 1, March 2025
Pages:
1-6
Received:
14 March 2025
Accepted:
31 March 2025
Published:
19 April 2025
DOI:
10.11648/j.ab.20251301.11
Downloads:
Views:
Abstract: Vitamin D has been recognized for several decades as an important player in bone metabolism. Beyond these classic effects on mineral metabolism, it has numerous extra-osseous effects, including effects on the cardiovascular system. Indeed, several clinical studies suggest a link between vitamin D deficiency and cardiovascular mortality. The general objective is to evaluate the relationship between vitamin D levels and lipid parameters in patients at Fann University Hospital. Included in this study were 214 patients who came to the laboratory and whose vitamin D dosage was requested between December 2023 and April 2024. Lipid profile parameter dosages were performed with the Architect Ci4100 and vitamin D with Iflash 3000. Correlations between vitamin D levels and blood lipids were assessed by descriptive statistical analysis and Spearman's correlation test. The mean age of our population was 60±17 years and the sex ratio was 0.51. The distribution of patients according to the lipid profile showed that 72.42% of the subjects had a lipid abnormality with a predominance of hypo HDL-cholesterolemia (39.71%). Our study showed a positive and significant correlation between low vitamin D levels and low HDL-cholesterol levels. In contrast, no strong link was found with the levels of total cholesterol, triglycerides and LDL-cholesterol. These results highlight the importance of monitoring vitamin D levels in patients with dyslipidemia, and pave the way for future research on the potential role of vitamin D in cardiovascular risk management.
Abstract: Vitamin D has been recognized for several decades as an important player in bone metabolism. Beyond these classic effects on mineral metabolism, it has numerous extra-osseous effects, including effects on the cardiovascular system. Indeed, several clinical studies suggest a link between vitamin D deficiency and cardiovascular mortality. The general...
Show More
Research Article
Disorders of Biochemical Parameters Associated with Protein-energy Malnutrition in Adults Hospitalized in Ouagadougou, Burkina Faso
Issue:
Volume 13, Issue 1, March 2025
Pages:
7-15
Received:
19 March 2025
Accepted:
7 April 2025
Published:
28 April 2025
DOI:
10.11648/j.ab.20251301.12
Downloads:
Views:
Abstract: The assessment of the nutritional status of the hospitalized person is often considered secondary to the pathologies justifying hospitalization. A multicenter study conducted in six Belgian hospitals showed a risk of malnutrition in just over one in five patients. This malnutrition during hospitalization is more frequent in the elderly and those with chronic pathologies. However, malnutrition is a very serious prognostic factor for hospitalized people because it multiplies the risk of infectious pathologies by two to six and the duration of hospitalization by two to four. This study is part of the promotion of better holistic care at the Yalgado OUEDRAOGO University Hospital Center (YO UHC) in Ouagadougou, Burkina Faso, which includes the assessment of the nutritional status of hospitalized people. A descriptive cross-sectional study with analytical aims over a period of nine (09) months was conducted. The study population consisted of people aged 50 and over in outpatient or hospitalized patients, recruited in the internal medicine department of YO UHC. Study variables included anthropometric parameters, blood count, specific nutritional and inflammatory proteins such as transthyretin, albumin, orosomucoid and C-reactive protein (CRP), as well as nutritional indexes such as the Body Mass Index (BMI), the Mini nutritional assessment (MNA) and the Prognostic inflammatory and nutritional index (PINI). Statistical analysis was performed using Epi info version 7.2.1.0. Were included 102 individuals consisted of 42 men and 60 women with a male/female sex ratio of 0.7. The mean age was 63±9 years with extremes ranging from 50 to 72 years. The mean values of the various anthropometric parameters were significantly lower in hospitalized patients compared to outpatients (p<10-3) with 50% of hospitalized patients having a BMI<21 kg/m2. The mean value of the MNA score was 13.67±4.83 in hospitalized patients compared to 21.57±3.24 in outpatients (p<10-4). The mean values of nutritional proteins were significantly lower in hospitalized patients with 55.9% having albuminemia <35 g/L and 47% having transthyretin <200 mg/L. For inflammatory proteins, the mean values were significantly higher in hospitalized patients with 29.4% having CRP >20 mg/L. The combined assessment reports that 50% of hospitalized patients had a PINI>1, of which approximately 15% had a vital risk (PINI>30). The results show a high frequency of protein-energy malnutrition accompanied by inflammatory syndrome in hospitalized people. Therefore, it is important to monitor the nutritional status of hospitalized people in order to avoid complications and an increase in the length of hospitalization.
Abstract: The assessment of the nutritional status of the hospitalized person is often considered secondary to the pathologies justifying hospitalization. A multicenter study conducted in six Belgian hospitals showed a risk of malnutrition in just over one in five patients. This malnutrition during hospitalization is more frequent in the elderly and those wi...
Show More
,
Thioune Ndeye Mareme
